Myristoleic acid

CAS No. 544-64-9

Myristoleic acid ( (Z)-Tetradec-9-enoic acid; cis-9-tetradecenoic acid; 9-Tetradecenoic acid )

Catalog No. M28356 CAS No. 544-64-9

Myristoleic acid is a cytotoxic component in the extract from Serenoa repens. Myristoleic acid induces apoptosis and necrosis in human prostatic LNCaP cells.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
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Biological Information

  • Product Name
    Myristoleic acid
  • Note
    Research use only, not for human use.
  • Brief Description
    Myristoleic acid is a cytotoxic component in the extract from Serenoa repens. Myristoleic acid induces apoptosis and necrosis in human prostatic LNCaP cells.
  • Description
    Myristoleic acid is a cytotoxic component in the extract from Serenoa repens. Myristoleic acid induces apoptosis and necrosis in human prostatic LNCaP cells.(In Vitro):Myristoleic acid induces both necrosis (100 μg/mL, 81.8%) and apoptosis (100 μg/mL, 89.5%) in LNCaP cells . Myristoleic acid inhibited RANKL-induced osteoclast formation in vitro, especially, at later stages of differentiation. (In Vivo):Myristoleic acid (2 mg/kg, IP every 24 h for 4 days) prevents RANKL-induced bone loss and osteoclast formation in mice .
  • Synonyms
    (Z)-Tetradec-9-enoic acid; cis-9-tetradecenoic acid; 9-Tetradecenoic acid
  • Pathway
    Apoptosis
  • Target
    Apoptosis
  • Recptor
    SARS-CoV-2
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    544-64-9
  • Formula Weight
    226.4
  • Molecular Formula
    C14H26O2
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    CCCC\C=C/CCCCCCCC(O)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Han SH, et al. Structure-Based Optimization of ML300-Derived, Noncovalent Inhibitors Targeting the Severe Acute Respiratory Syndrome Coronavirus 3CL Protease (SARS-CoV-2 3CLpro). J Med Chem. 2022 Feb 24;65(4):2880-2904.
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